The mediodorsal thalamus as a higher order thalamic relay nucleus important for learning and decision-making
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The mediodorsal thalamus as a higher order thalamic relay nucleus important for learning and decision-making
Recent evidence from monkey models of cognition shows that the magnocellular subdivision of the mediodorsal thalamus (MDmc) is more critical for learning new information than for retention of previously acquired information. Further, consistent evidence in animal models shows the mediodorsal thalamus (MD) contributes to adaptive decision-making. It is assumed that prefrontal cortex (PFC) and me...
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The mediodorsal thalamic nucleus (MDT) is a higher order thalamic nucleus and its role in cognition is increasingly well established. Interestingly, components of the MDT also have a somewhat unique sensory function as they link primary olfactory cortex to orbitofrontal associative cortex. In fact, anatomical evidence firmly demonstrates that the MDT receives direct input from primary olfactory...
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It has been proposed that the thalamus is composed of at least two types of nuclei. First-order relay nuclei transmit signals from the periphery to the cortex while higher order nuclei may route information from one cortical area to another. Although much is known about the functional properties of relay neurons in first-order nuclei, little is known about relay neurons belonging to higher-orde...
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ژورنال
عنوان ژورنال: Neuroscience & Biobehavioral Reviews
سال: 2015
ISSN: 0149-7634
DOI: 10.1016/j.neubiorev.2015.03.001